The Georgia Cancer Coalition - Cancer Research Awards


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Wen-Chin Huang, PhD
Georgia Cancer Coalition
Cancer Research Fund Awardee

Assistant Professor
Emory University School of Medicine
1365B Clifton Rd, NE, B5105
Atlanta, Georgia 30322

Website:	http://urology.emory.edu/mut/mutfs/
Email:	whuang3@emory.edu
Phone:	404-778-3683
Fax:	404-778-3965

Title of Project:
Targeting beta2-microglobulin signaling axis in human prostate cancer stem cells

Aims of Project:

To use beta2M mAb as a novel therapeutic approach to kill prostate cancer stem cells.
To interrupt beta2M and is signaling axis in prostate cancer stem cells in vitro and in vivo.
To determine the molecular mechanism of beta2M mAb-regulated signaling pathways in prostate cancer stem cells.